Premium Retinoid Ester Active Ingredient

Hydroxypinacolone Retinoate (HPR)

Retinoid precision.
Skin-kind delivery.

Bakunova offers premium cosmetic active ingredients manufactured under GMP quality standards, delivering consistent, reliable, and high-performance solutions for global skincare brands.

INCI Hydroxypinacolone Retinoate
CAS No. 893412-73-2
Type Retinoid Ester
Next-generation retinoid ester
Hydroxypinacolone Retinoate — molecular structure and retinoid science
C₂₆H₃₈O₄
Molecular Formula
MW: 418.58 g/mol
Why Hydroxypinacolone Retinoate

Science-Backed Performance

A next-generation retinoid ester targeting key biological pathways involved in skin aging, renewal, pigmentation control, and sebum regulation — with superior tolerability.

Anti-Aging & Skin Renewal

Directly activates retinoid receptors to stimulate collagen and elastin synthesis, accelerate cell turnover, and visibly reduce fine lines and wrinkles.

Retinol-Like Efficacy with Superior Tolerability

Delivers comparable retinoid activity to retinol via the same biological pathway with significantly reduced irritation, redness, and skin sensitivity.

Pigmentation & Tone Uniformity

Modulates melanin synthesis pathways to address hyperpigmentation, dark spots, and uneven skin tone — promoting a visibly brighter complexion.

Sebum Regulation & Acne Control

Regulates sebaceous gland activity and supports pore refinement, helping manage acne-prone skin without the harsh side effects of conventional retinoids.

From retinoid ester to next-generation delivery
Value-Added HPR Solutions

Ready-to-Formulate Solutions

Each HPR format is engineered for enhanced skin penetration, superior stability, and seamless integration into premium cosmetic formulations.

Liposomal HPR
01

Liposomal HPR

Phospholipid bilayer encapsulation for targeted, controlled release and superior dermal penetration with enhanced skin compatibility.

  • Controlled Release
  • Deep Penetration
  • High Bioavailability
HPR Microemulsion
02

HPR Microemulsion

Thermodynamically stable nano-droplet system providing transparent, elegant formulation aesthetics with excellent active solubilization.

  • Nano-droplet Stability
  • Transparent Finish
  • Easy Incorporation
HPR Beta CD Complex
03

HPR Beta CD Complex

β-Cyclodextrin inclusion complex dramatically improves aqueous solubility and photo-stability, ideal for water-based formulations.

  • Improved Solubility
  • Photo-Stable
  • Water-Compatible
HPR Solid Lipid Nanoparticles
04

HPR Solid Lipid Nanoparticles

SLN matrix provides prolonged sustained release, exceptional oxidative stability, and extended shelf life — optimal for anti-aging serums.

  • Sustained Release
  • Oxidative Stability
  • Extended Shelf Life
HPR Ionic Liquid (CAGE)
05

HPR Ionic Liquid (CAGE)

Choline-and-geranic acid ionic liquid complex unlocks unprecedented transdermal delivery without conventional solvents for maximum penetration.

  • Transdermal Delivery
  • Solvent-Free
  • Max Penetration
Science-Backed Innovation

Proven ingredients. Advanced delivery.

Enhanced Stability

Improved bioavailability and shelf life.

Superior Performance

Better penetration, efficacy & safety.

Formulation Excellence

Ready-to-use solutions. Time-saving. Cost-effective.

Ready to Formulate?

Bring HPR Into
Your Next Formula

From premium Hydroxypinacolone Retinoate active to advanced skincare solutions — Bakunova's customized delivery technologies enhance retinoid efficacy, stability, controlled release, and skin performance for next-generation differentiated formulations.