Development Pipeline

Advanced Dermatology Pipeline

Next-Generation Dermatology Innovations

Bakunova is developing a pipeline of next-generation dermatology solutions targeting acne, psoriasis, vitiligo, skin hyperpigmentation, and skin ageing by integrating scientifically validated active ingredients with the Xnova™ Technology Platform.

Our development strategy combines advanced delivery science with formulation engineering to enhance ingredient stability, skin penetration, targeted skin deposition, and biological performance.

Each pipeline programme undergoes a comprehensive nonclinical evaluation using internationally accepted in vitro and ex vivo models, including:

• Skin permeation and skin retention studies using human skin
• Mechanistic evaluation through biomarker and cytokine pathway analysis
• Cellular efficacy studies using disease-relevant human cell lines
• Skin irritation, skin corrosion, and cytotoxicity assessments performed in accordance with applicable OECD Test Guidelines using reconstructed human epidermis (RHE) models and validated cell-based systems
• Integrated scientific assessment to support formulation optimization and technology validation

These studies generate a robust scientific evidence package that supports technology performance, product differentiation, and commercial development.

Selected pipeline programmes are available for strategic partnerships, co-development, and commercial licensing.